Successful and pleasurable sex relies on uninterrupted erectile function in men, and if this process falters, it is termed erectile dysfunction, impacting sexual satisfaction.
Top Apotheke can offer you the required medication to treat erectile dysfunction (ED), which you can buy online from their website.
Consider buying Levitra
Levitra (vardenafil) is a branded drug addressing erectile dysfunction, a widespread condition. Classified as a PDE-5 inhibitor, Levitra helps by easing penile smooth muscles, promoting blood flow for erection.
Remember, Levitra does not cure ED. Stimulation is essential for its effectiveness. Both Levitra and its generic counterpart (vardenafil) are offered in various doses:
- 2.5 milligrams
- 5 milligrams
- 10 milligrams
- 20 milligrams.
The best dose will depend on your:
- Age
- Health
- Medications.
What are other alternatives to treat ED?
Numerous oral treatments exist for erectile dysfunction. However, the sole approved US medication is sildenafil (Viagra), a PDE 5 enzyme inhibitor. Unapproved therapies, found in the US and elsewhere, vary in proven efficacy and availability, which are:
- Tadalafil (Cialis)
- Yohimbine
- Phentolamine
- Trazodone
- Apomorphine
- Neutraceuticals.
PDE5 inhibitors relax penile tissues upon sexual stimulation, improving erection capability. Data shows that 69% of people can get treated by using Sildenafil (Viagra) and can enjoy their sex life.
Why look for another pill?
Erection might be insufficient, and sildenafil (Viagra) can occasionally be ineffective. Vardenafil (Levitra) shares structural similarities with sildenafil, but tadalafil (Cialis) differs significantly.
Vardenafil’s biochemically potency, nearly tenfold that of sildenafil, allows for lower dosages to help penile erection, potentially minimizing side effects.
Selectivity refers to a drug’s ability to bind to a particular enzyme, such as PDE5, in penile tissues. Compared to sildenafil and tadalafil (Cialis), Vardenafil (Levitra) demonstrates higher selectivity for PDE5, requiring a lower dose and possibly fewer side effects.
Tadalafil uniquely targets PDE5 and PDE11 with precision. However, limited knowledge surrounds PDE11, which is present in the heart, brain’s pituitary gland, and testicles.
Medication duration in the bloodstream is guided by pharmacokinetics, notably half-life.
- Sildenafil (Viagra) has got a 4-hour half-life
- Vardenafil (Levitra) has got 4 to 6 hours of half-life
- Tadalafil (Cialis) has a substantial 17.5 hours of half-life.
Vardenafil’s prolonged half-life suggests potential extended action compared to sildenafil, yet clinical implications remain uncertain.
Tadalafil, with the lengthiest half-life, offers the advantage of decoupling sexual activity from immediate medication consumption. This flexibility stems from its prolonged presence in the body, which can afford the freedom to engage in intimacy without immediate reliance on the drug.
Pharmacokinetics, encompassing half-life, govern a drug’s presence in the bloodstream. Vardenafil’s prolonged half-life hints at potential prolonged effects versus sildenafil, though clinical implications are uncertain. Tadalafil, with the longest half-life, enables detachment of sexual activity from immediate drug intake, offering the liberty for intimacy without immediate dependency, owing to its enduring bodily presence.
Conclusion
Many people worldwide may be silently suffering from ED. However, today we have many alternatives available. In the pursuit of managing erectile dysfunction, exploring safe medications is very important.
Sildenafil, vardenafil, and tadalafil offer distinct benefits influenced by pharmacokinetics and selectivity. Consulting a healthcare professional ensures informed decisions, improves intimacy and enhances the quality of life.
